Synthesis and Characterization of Novel 4-[3,5-bis(trifluoromethyl)phenyl]-6-(Substituted phenyl)-1,6-dihydropyrimidine-2-thiol

Synthesis and Characterization of Novel 4-[3,5-bis(trifluoromethyl)phenyl]-6-(Substituted phenyl)-1,6-dihydropyrimidine-2-thiol


Vyas T, Vyas K


Abstract

Synthesis of various dihydropyrimidine-2-thiol from (E)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(substituted)phenylprop-2-en-1-one and thiourea in presence of NaOH. The structures of the synthesized compounds were confirmed on the basis of spectral and elemental analysis.


Keywords

Chalcones, (E)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(substituted)phenylprop-2-en-1-one, thiourea, dihydropyrimidine-2-thiol compounds.


Cite This Article

Vyas T, Vyas K, Synthesis and Characterization of Novel 4-[3,5-bis(trifluoromethyl)phenyl]-6-(Substituted phenyl)-1,6-dihydropyrimidine-2-thiol, International Journal for Pharmaceutical Research Scholars, 2012, 1(2), 481-484.

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