Synthetic Advances and Biological Activities of 4-Hydroxy Coumarin Derivatives

Synthetic Advances and Biological Activities of 4-Hydroxy Coumarin Derivatives


Karia DC, Pancholi KS, Varu RA


Abstract

Synthesis of a series of 4-hydroxy-6-methyl-3-(substituted methyl)-2H-chromen-2-one. (4a-g) was achieved from different secondary amine, formaldehyde and 4-hydroxy-6-methyl-2H-chromen-2-one using Con HCl added and refluxed within 8 hrs with good yield. The structures of the products were supported by FTIR, PMR and mass spectral data.


Keywords

4-hydroxy-6-methyl-3-(substituted methyl)-2H-chromen-2-one; secondary amine, 2-Aformaldehyde, only refluxed


Cite This Article

Karia DC, Pancholi KS, Varu RA, Synthetic Advances and Biological Activities of 4-Hydroxy Coumarin Derivatives, International Journal for Pharmaceutical Research Scholars, 2013, 2(4), 139-142.

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