Recent Trends in Formulation and Applications of Nanoparticles
Ankita Chamoli, Lakshmayya, Pranshu Tangri
Nanoparticles are defined as particulate dispersions or solid particles with a size in the range of 10-1000nm. The drug is dissolved, entrapped, encapsulated or attached to a nanoparticle matrix. Depending upon the method of preparation, nanoparticles, nanospheres or nanocapsules can be obtained. Nanocapsules are systems in which the drug is confined to acavity surrounded by a unique polymer membrane, while nanospheres are matrix systems in which the drug is physically and uniformly dispersed.The major goals in designing nanoparticles as a delivery system are to control particle size, surface properties and release of pharmacologically active agents in order to achieve the site-specific action of the drug at the therapeutically optimal rate and dose regimen. In this article we discuss about nanoparticles and its formulation and evaluation with current strategies.
Nanoparticles, Nanospheres, Nanocapsules, Particulate dispersions
Cite This Article
Ankita Chamoli, Lakshmayya, Pranshu Tangri, Recent Trends in Formulation and Applications of Nanoparticles, International Journal for Pharmaceutical Research Scholars, 2013, 2(4), 339-351.