Synthesis, Identification and Antimicrobial Activity of Some Novel Quinazolinone Derivatives and its Metal Complexes
Mamtora MJ, Mahetar JG, Manavar RB, Jadeja JJ, Shah MK*
In the present study O, N, O-donating ligand was prepared from the condensation of 2-aminobenzohydrazide and o-vanillin. The chemical structures were confirmed by Mass, ESI Mass, IR, 1H NMR, 13C NMR spectroscopy and Elemental analysis. Metal complex of this ligand is neither air- nor moisture-sensitive. The compounds were tested antimicrobial activity against the four bacterial and four fungal strains. The metal complexes display effective inhibitory action than ligand against test organisms.
Dihydroquinazolinone, Schiff Base, Metal Complexes, Antimicrobial Activity
Cite This Article
MamtoraM M. J., Mahetar, J. G., Manavar, R. B., Jadeja, J. J., & Shah, M. K. (2015). Synthesis, Identification and Antimicrobial Activity of Some Novel Quinazolinone Derivatives and its Metal Complexes, International Journal for Pharmaceutical Research Scholars, 4(1), 38-44.