Study of Prescribing Pattern of Fixed Dose Combinations in the Medicine Department of a South Indian Tertiary Care Teaching Hospital

Study of Prescribing Pattern of Fixed Dose Combinations in the Medicine Department of a South Indian Tertiary Care Teaching Hospital


Londhe SP*, Basavanagowda GM, Gowraw NS, Roopashree PM, Baishnab S


Abstract

To study the prescribing pattern of fixed dose combinations in the medicine department of South Indian tertiary care teaching hospital. The study was a prospective, observational study. The study was conducted for a period of 6 months. Data required to study the prescription pattern was collected from the inpatient case sheets in the medicine department and subjected to assess the pattern of FDCs prescribed and also rationality of FDCs by using WHO and DCGI drug list. Among the 100 patient case sheets 284 FDCs were found. Out of 284 FDCs most commonly prescribed FDCs belonged to antimicrobial group 66(23%).

  • 95(33.45%). FDCs prescribed without indications
  • 31(10.91%) FDCs prescribed with inappropriate dose.

Out of 284 FDCs, 202(71.12%) FDCs were present in the DCGI list and only 4(1.40%) FDCs were present in the WHO essential medicine list. In this study most of the FDCs failed to meet the WHO guidelines. Most of the physicians are unaware of WHO and DCGI guidelines. Pharmaceutical manufacturer, however continue to produce huge amount of fixed dose combinations and continue promoting them with vigour. The DCGI should put tremendous pressure on pharmaceutical companies on withdrawal of irrational drugs from market as it affects a large number of drug units.


Keywords

Fixed-Dose Combination, DCGI List, WHO Essential Medicine List, Rationality, Prescribing Pattern


Cite This Article

Londhe, S. P., Basavanagowda, G. M., Gowraw, N. S., Roopashree, P. M., & Baishnab, S. (2015). Study of Prescribing Pattern of Fixed Dose Combinations in the Medicine Department of a South Indian Tertiary Care Teaching Hospital, International Journal for Pharmaceutical Research Scholars, 4(1), 168-177.

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