Preparation and Characterization of a Series of Narrative Pyrimidine Derivatives
Vakhariya C, Ram H*, Shah V
Synthesis of a series of 1,2,3,4-tetrahydro-4-(substitutedphenyl)-6-methyl-2-oxo-N-(pyridin-3-yl)pyrimidine-5-carboxamide (4a-h) was achieved from different Aldehydes, N-(pyridin-3-yl)-3-oxo-butanamide and urea using catalytical amount of concentrated hydrochloric acid in ethanol the product obtained was isolated and recrystallized from ethanol. So to the fine yield. The structures of the products were supported by FTIR, 1H NMR and mass spectral data.
N-(Pyridin-3-yl)-3-Oxo-Butanamide, Aldehyde, Hydrochloric Acid, Urea Only Refluxed
Cite This Article
Vakhariya, C., Ram, H., & Shah, V. (2015). Preparation and Characterization of a Series of Narrative Pyrimidine Derivatives, International Journal for Pharmaceutical Research Scholars, 4(4), 141-145.