A Review on Sustained Release Oral Drug Delivery System

Author(s)

Thombre, N.A., Aher, A.S., Wadkar, A.V., Kshirsagar, S.J.

Author's Affiliation

Abstract

The advantage of administering a single dose of a drug that is released over an extended period of time instead of numerous doses is now a day’s area of interest for formulation scientists in Pharmaceutical industry. There are several advantages of sustained release drug delivery over conventional dosage forms like improved patient compliance due to less frequent drug administration, maximum utilization of the drug, increased safety margin of potent drug, reduction of fluctuation in steady-state drug levels, reduction in healthcare costs through improved therapy and shorter treatment period. Sustained release drug delivery system mainly classified into continuous release, delayed release and delayed transit and continuous. The matrix controls the release rate of drug. The matrices used may be of hydrophilic, hydrophobic, mineral, or biodegradable types. The drug release rate can be studied by in-vitro dissolution studies.

Keywords

Sustained Release, Matrix Tablet, Polymers, Diffusion

Cite This Article

Thombre, N.A., Aher, A.S., Wadkar, A.V., Kshirsagar, S.J. (2015). A Review on Sustained Release Oral Drug Delivery System, International Journal for Pharmaceutical Research Scholars (IJPRS), 4(2), 361-371.