Anticonvulsant Activity of Some Novel Substituted Thiazolidinone Derivatives against Maximal Electro Shock Induced Seizure

Author(s)

Ahmed, O., Sharma, P., Singhvi, I.

Author's Affiliation

Abstract

The main objective of this study is to synthesize 2-(substituted phenyl)-3-[{4-(1-naphthyl) - 1, 3 -thiazol-2-yl} amino] -4-oxo- 1, 3) -thiazolidin-5-yl] acetic acid (TA₁-TA₁₀) from 1-acetyl naphthalene. The synthesized compound, characterized on the basis of satisfactory analytical and spectral (IR, H¹NMR) data, have shown moderate to good anticonvulsant activity.

Keywords

Antihyperglycemic activity, 1-Acetylnaphthalene, Thiazoles, Thiazolidinones

Cite This Article

Ahmed, O., Sharma, P., & Singhvi, I. (2014). Anticonvulsant Activity of Some Novel Substituted Thiazolidinone Derivatives against Maximal Electro Shock Induced Seizure. International Journal for Pharmaceutical Research Scholars, 3(1), 289-294.