Biological Evaluation of Chukrasia tabularis A. Juss Leaves for Anti-Diabetic and Anti-Arthritic Activities

Author(s)

Tejaswi, J.K.D., Govinda R.R., Yogitha, M.

Author's Affiliation

Abstract

The plant under evaluation Chukrasia tabularis, a plant of Meliaceae, which is usually found, scattered in evergreen rainforest. From the review of literature, it was reported that various pharmacological activities were reported on Chukrasia tabularis A. Juss. So far Anti-Diabetic & Anti-Arthritic activities are not reported on the plant. In view of this, the present study was aimed to carryout biological evaluation of the obtained Ethyl Acetate fraction for Anti-Diabetic (In vitroα-Amylase Inhibition Assay with Acarbose as standard and Ex vivo Rat Everted Sac Model method with Acarbose as standard) and Anti-Arthritic activities (In vitro Protein Denaturation Assay method with Diclofenac sodium as standard) respectively. The results were compared with the standard using statistical method. The Anti-Diabetic activities of Ethyl acetate fraction showed significant activity when compared to standard. The Anti Arthritic activity of the Ethyl acetate showed more protection activity than the standard.

Keywords

Chukrasia Tabularis, Flavonoids, Meliaceae, Anti-Diabetic, Anti-Arthritic

Cite This Article

Tejaswi, J.K.D., Govinda R.R., Yogitha, M. (2016). Biological Evaluation of Chukrasia tabularis A. Juss Leaves for Anti-Diabetic and Anti-Arthritic Activities, International Journal for Pharmaceutical Research Scholars (IJPRS), 5(4), 73-79.