Capsaicin in Pain Management

Author(s)

Patil, S.T., Bhogale, V., Sharma, B.S., Adepu, A.R., Ghawat, A.G.

Author's Affiliation

Abstract

Capsaicin is a pungent highly domesticated fat soluble alkaloid having its origin from Bolvia and Brazil. It acts by binding TRPV1 and shows wide applications in relief from neuropathic and musculoskeletal pain, post herpetic neuralgia, arthritic pain and cluster headache. Capsaicin has analgesic and anti-inflammatory properties and has been used in topical creams and gels for treating pain due to various conditions. Adverse effects include local discomfort characterized by burning, stinging and redness of the skin but systemic events are rare. Capsaicin is under development therapy for various diseases, it may develop as a new treatment therapy for a number of diseases in near future. A review is mainly focusing on its origin, chemistry, use, toxicity, mechanism, application and case study.

Keywords

Capsaicin, Capsaicinoids, Pain, Application, Case Study

Cite This Article

Patil, S.T., Bhogale, V., Sharma, B.S., Adepu, A.R., Ghawat, A.G. (2015). Capsaicin in Pain Management, International Journal for Pharmaceutical Research Scholars (IJPRS), 4(2), 333-345.