Detection of ESBL Producing Gram Negative Bacteria and its Sensitivity Pattern in Intensive Care Unit

Author(s)

Vasumathi, A., Thenmozhi, P.R., Senthamarai, S., Ramani, C.P., Jagadeesan, R.

Author's Affiliation

Abstract

Extended Spectrum of Beta Lactamase (ESBL) producing organisms are the major problem and great challenge to clinicians, microbiologists and infection control professionals. These enzymes compromise the efficacy of all beta lactums by hydrolysing the beta lactum ring. In this study, total of 95 gram negative isolates were isolated from various clinical samples from ICU patients and subjected for antibiotic susceptibility testing. These isolates were screened for ESBL and confirmed by combined disc diffusion method. Out of 95 GNB, 37 were ESBL producers. They are highly sensitive to imipenem, followed by ofloxacin, cefoperazone-sulbactum, amikacin and amoxyclav. Proper antibiotic usage and promoting awareness will help in preventing the multidrug resistance among the organisms.

Keywords

ESBL, GNB, ICU

Cite This Article

Vasumathi, A., Thenmozhi, P.R., Senthamarai, S., Ramani, C.P., Jagadeesan, R. (2016). Detection of ESBL Producing Gram Negative Bacteria and its Sensitivity Pattern in Intensive Care Unit, International Journal for Pharmaceutical Research Scholars (IJPRS), 5(1), 84-89.