Development and Characterization of Topical Herbal Formulation of Curcuma Longa Extracts Using Plastibase Technology

Author(s)

Punit, P., Harnisha, P., Akanksha, P., Hetal, P., Vivek, V., Pragna, S.

Author's Affiliation

Abstract

Turmeric (curcuma longa) was known for the Remedy as a healing agent for many years. The grinded rhizomes of Curcuma longa (L.) were extracted with methanol, methanol-water, and water respectively. These extracts were dried. The ointment formulations containing extracts of the turmeric in above-mentioned solvents were formulated, optimized and evaluated for various parameters and their wound healing activity was studied on experimentally induced excision wounds in Wistar albino rats. The use of various topical bases and its comparative study was performed with plastibase ointment. The plastibase was employed at three different concentrations (5%, 10% and 15% w/v). The amount of liquid paraffin was also optimized based in plastibase granules. The results showed that the ointment prepared using an alcoholic extract of Curcuma longa with plastibase granules revealed best-wound healing activity than ointment prepared from other extracts and marketed formulation. The results of short-term stability study showed stable characteristics of the developed formulation.

Keywords

Curcumin, Plastibase, Wound healing action, Stability study

Cite This Article

Punit, P., Harnisha, P., Akanksha, P., Hetal, P., Vivek, V., Pragna, S. (2017). Development and Characterization of Topical Herbal Formulation of Curcuma Longa Extracts Using Plastibase Technology. International Journal for Pharmaceutical Research Scholars (IJPRS), 6(2), 8-18.