Evaluation of the Antidiarrheal Activity of Ethanolic Extract of Diospyros virginiana in Rats

Author(s)

Priya, S., Nethaji, S., Sindhuja, R.

Author's Affiliation

Abstract

The ethanolic extract of the leaves and bark of Diospyros virginiana was screened for antidiarrheal effects. The extract was evaluated for castor oil- induced diarrhea and intestinal transit in rats. Diospyros virginiana significantly dose-dependently reduced frequency of stooling in castor oil-induced diarrhea and intestinal motility in rats. Ethanolic leaves extracts reduces diarrheal burden than ethanolic bark extract. These findings suggest that the ethanolic extract of the leaves and bark of Diospyros virginiana may contain some biologically active ingredients that are active for the treatment of diarrhea in herbal traditional medicine.

Keywords

Antidiarrheal activity, Castor oil, Char coal meal, Ethanolic extracts

Cite This Article

Priya, S., Nethaji, S., & Sindhuja, R. (2014). Evaluation of the Antidiarrheal Activity of Ethanolic Extract of Diospyros virginiana in Rats. International Journal for Pharmaceutical Research Scholars, 3(1), 74-78.