Field Flow Fractionation Technique- A Review

Author(s)

Chalak, N., Khanvilkar, V., Ayare, P.

Author's Affiliation

Abstract

Field Flow Fractionation (FFF) is a family of analytical technique developed specifically for separation and characterization of macromolecules, supramolecular assemblies and colloids. It combines the effect of laminar flow profile with physical field applied which is perpendicular to flow of carrier liquid. FFF is becoming popular as the researchers are learning its potential. The technique is also versatile and can be easily coupled with other analytical techniques like chromatography, spectrometry etc. Present review underlines the basic principle involved and theory of FFF along with its types like thermal FFF, flow FFF etc. Further the review elaborates its application to characterize natural, biological and synthetic polymers as well as proteins including analysis of lipid DNA complexes.

Keywords

Field Flow Fractionation (FFF), macromolecules, Separation, Sedimentation FFF, Thermal FFF, Flow FFF, Electrical FFF

Cite This Article

Chalak, N., Khanvilkar, V., & Ayare, P. (2014). Field Flow Fractionation Technique - A Review. International Journal for Pharmaceutical Research Scholars (IJPRS), 3(4), 122-132.