Lipid Profile in Chronic Renal Failure Patients – Pre and Post Hemodialysis

Author(s)

Sandesh, T., Tilak, M.A.

Author's Affiliation

Abstract

The Chronic Kidney Disease is characterized by specific metabolic abnormalities of plasma lipids both qualitatively and quantitatively. Most common lipid abnormalities encountered are increased serum triglycerides and decreased serum HDL cholesterol with small alteration of other lipoprotein fraction in serum and in dialysis patients there is more of a dyslipidemia rather than hyperlipidemia. This may be a significant risk factor for vascular complications leading to increased morbidity and mortality in CKD patients. So Aim of study was to assess cardiovascular risk in chronic renal failure (CRF) patients by studying pre and post hemodialysis Serum Total Cholesterol, HDL-Cholesterol, LDL-Cholesterol, Triglyceride levels in CRF patients. Total Cholesterol, Triglyceride, LDL-C showed highly significant decreased in mean concentration in post-hemodialysis than in pre- hemodialysis samples of CRF patients. HDL-C showed significant elevation in post-hemodialysis than in pre- hemodialysis samples of CRF patients. Thus this study demonstrates that there is a decreased risk of cardiovascular complications in patients undergoing hemodialysis and decreased risk of cardiovascular improves the general wellbeing and lower the cost of health care in hemodialysis patients.

Keywords

Chronic renal failure (CRF), Chronic Kidney Disease (CKD), HDL-Cholesterol (HDLC), LDL-Cholesterol (LDLC)

Cite This Article

Sandesh, T., Tilak, M.A. (2015). Lipid Profile in Chronic Renal Failure Patients - Pre and Post Hemodialysis, International Journal for Pharmaceutical Research Scholars (IJPRS), 4(1), 236-241.