Microemulsion Based Gel: A Novel Approach in Delivery of Hydrophobic Drugs

Author(s)

Wani, R.R., Patil, M.P., Dhurjad, P., Chaudhari, C.A., Kshirsagar, S.J.

Author's Affiliation

Abstract

Microemulsion based gel is an emerging topical delivery system contains both microemulsion as well as gel. Microemulsion based gels are either oil in water or water in oil type of microemulsion, which is gelled by mixing it with suitable gelling agent. Incorporation of microemulsion into gel increases its stability and makes it dual control release system. Presence of gel phase makes it a non-greasy, non-sticky and smooth appearance which favors better patient compliance. These reviews give brief knowledge about microemulsion based gel including its properties, advantages, formulation considerations, and its recent advances in research field.  In preparation of microemulsion based gel the factors such as selection of gelling agent, oil phase, surfactants influencing the stability and efficacy of microemulsion based gel are discussed. All justifications are described in accordance with the research work carried out by various research scientists. These brief reviews on formulation method have been included. Current research works that carried out on microemulsion based gel are also discussed and highlighted the wide utility of microemulsion based gel in topical drug delivery system. After the brief study, it can be concluded that the microemulsion based gels appear better and effective drug delivery system as compared to other topical drug delivery system.

Keywords

Microemulsion, Gel, Topical Delivery

Cite This Article

Wani, R.R., Patil, M.P., Dhurjad, P., Chaudhari, C.A., Kshirsagar, S.J. (2015). Microemulsion Based Gel: A Novel Approach in Delivery of Hydrophobic Drugs, International Journal for Pharmaceutical Research Scholars (IJPRS), 4(2), 397-410.