Novel Approach to Synthesis Silver Nanoparticles using Leaf Extract of Trichosanthes cucumerina L. and its Antibacterial Activity

Author(s)

Piramila, B. H. M., Prabha, A. L., Nandagopalan, V.

Author's Affiliation

Abstract

Green synthesis of nanoparticles is evolving into an important branch of nanotechnology, because biological methods are considered safe and ecologically sound for the nanomaterial fabrication as an alternative to conventional physical and chemical methods. In this work, we have investigated a simple and eco-friendly biosynthesis of silver nanoparticles using Trichosanthes cucumerina L. leaf extract as reducing agent. The optical properties of silver nanoparticles have been measured using UV-VIS Spectroscopy. The absorption peak due to the Surface Plasmon Resonance of silver nanoparticles at wavelength of about 420nm was observed. Functional groups of the silver nanoparticles were confirmed through Fourier Transform Infrared Spectroscopy (FTIR). Scanning Electron Microscopy (SEM) analysis showed the morphology of the silver nanoparticles and the Energy Dispersive Spectroscopy (EDS) spectrum of the solution containing silver nanoparticles confirmed the presence of elemental silver signals. Structural characterization of synthesized silver nanoparticles carried out by X-ray diffractometer (XRD) shows that, the synthesized silver nanoparticles are face centered cubic crystalline. Further, these biologically synthesized nanoparticles were found to be highly toxic against different multi drug resistant human pathogens. Plant extract is very cost effective and ecofriendly and thus can be economic and effective alternative for the large scale synthesis of silver nanoparticles.

Keywords

Trichosanthes Cucumerina L, Silver Nanoparticles, Antibacterial Activity

Cite This Article

Piramila, B. H. M., Prabha, A. L., & Nandagopalan, V. (2014). Novel Approach to Synthesis Silver Nanoparticles using Leaf Extract of Trichosanthes cucumerina L. and its Antibacterial Activity. International Journal for Pharmaceutical Research Scholars, 3(2), 809-813.