Relation of Oxidative Stress with Serum Antioxidant Enzymes Level in Thalassemic Subjects

Author(s)

Choudhary, M., Vyas, R.K.

Author's Affiliation

Abstract

The association of oxidative stress with serum antioxidant enzymes are not uncommon encounter in thalassemic patients. Patients with this disease need repeated blood transfusion for survival. This may cause oxidative stress and tissue injury due to iron overload, altered antioxidant enzymes levels. The levels of antioxidant enzymes in thalassemia patients revels a significant change. The aim of this review is to scrutinize the relationship between oxidative stress and serum antioxidant enzymes level and degree of damage caused by oxidative stress. Studies published on the antioxidant enzymes level in thalassemia patients also showed variable results. The reports are controversial for the relation of oxidative stress with serum antioxidant enzymes status. Hence the present study is undertaken to determine the correlation of oxidative stress with these enzymes in thalassemia patients.

Keywords

Thalassemia, Serum Catalase, Superoxide Dismutase, Glutathione

Cite This Article

Choudhary, M., Vyas, R.K. (2015). Relation of Oxidative Stress with Serum Antioxidant Enzymes Level in Thalassemic Subjects, International Journal for Pharmaceutical Research Scholars (IJPRS), 4(1), 93-98.