Synthesis and Characterization of Novel 4-[3,5-bis(trifluoromethyl)phenyl]-6-(Substituted phenyl)-1,6-dihydropyrimidine-2-thiol

Author(s)

Vyas, T., Vyas, K.

Author's Affiliation

Abstract

Synthesis of various dihydropyrimidine-2-thiol from (E)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(substituted)phenylprop-2-en-1-one and thiourea    in presence of NaOH. The structures of the synthesized compounds were confirmed on the basis of spectral and elemental analysis.

Keywords

Chalcones, (E)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(substituted)phenylprop-2-en-1-one, thiourea, dihydropyrimidine-2-thiol compounds

Cite This Article

Vyas, T., Vyas, K. (2012). Synthesis and Characterization of Novel 4-[3,5-bis(trifluoromethyl)phenyl]-6-(Substituted phenyl)-1,6-dihydropyrimidine-2-thiol, International Journal for Pharmaceutical Research Scholars (IJPRS), 1(2), 481-484.