Synthesis, Spectral Studies and Biological Activities of 1-Acetyl-5-(substitutedphenyl)-{3-[4-(2-phenyl-4-p-hydroxybenzylidene-5-oxo-imidazol-1-yl)] phenyl}-4,5-dihydropyrazol derivatives

Author(s)

Patel, A. B., Patel, P. S.

Author's Affiliation

Abstract

1-acetyl-5-(substitutedphenyl)-{3-[4-(2-phenyl-4-p-hydroxybenzylidene-5-oxo-imidazol-1-yl)]phenyl}-4,5-dihydropyrazol have been prepared by the refluxation for three hours of 5-(substitutedphenyl)-[3-(4-{2-phenyl-4-(4-hydroxybenzylidene)-5-oxo-imidazol-1-yl})phenyl]-4,5-dihydropyrazol and Gly. aceticacid the intermediate A3 have been prepared by the refluxation for three hours of 4-(4-hydroxybenzylidene)-1-{4-[3-(substitutedphenyl)prop-2-enoyl]phenyl}-2-phenyl-imidazol-5-one with hydrazine hydrate in presence of ethanol the intermediate A2 synthesized by the condensation of  1-(4-acetylphenyl)-4-(4-hydroxybenzylidene)-2-phenyl-3,5-dihydro-imidazol-5-one with various aldehydes.

Keywords

Pyrazolines, Hydrazinehydrate, Benzaldehyde, Oxazolone, Pyrazol

Cite This Article

Patel, A. B., & Patel, P. S. (2013). Synthesis, Spectral Studies and Biological Activities of 1-Acetyl-5-(substitutedphenyl)-{3-[4-(2-phenyl-4-p-hydroxybenzylidene-5-oxo-imidazol-1-yl)] phenyl}-4,5-dihydropyrazol derivatives. International Journal for Pharmaceutical Research Scholars (IJPRS), 2(1), 138-141.